The GADD45A Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to GADD45, and GADD45A. This antibody recognizes Human, Mouse, Rat, and Hamster antigen. The GADD45A Antibody (C-term) has been validated for the following applications: ELISA, Flow Cytometry, and Western Blot.
Description
GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms